medflies in Tampa

P. Stadel Nielsen fdki at post2.tele.dk
Fri Jul 11 15:31:28 EDT 1997


Hello,
I have read you messages on the use of malathione and its possible
influence on other insects than the target species. I have got some data on
this substance at the mentioned address. As you see, malathione is far from
harmless to humans. 50% of young male rats are killed when given 290 mg/kg
body weight orally. Here in Denmark, it is forbidden to use malathione one
week before the plants/animal is to be used by humans, and the substance is
marked higly dangerous to honey bees.

Spreading a strong insecticide like this is without doubt doing terrible
harm to all insects in the area and therefore also to birds etc.

Kind regards
P. Stadel Nielsen, Denmark
fdki at post2.tele.dk
---------------
More data at:

http://ntp-db.niehs.nih.gov/NTP_Reports/NTP_Chem_H&S/NTP_Chem1/Radian121-75-
5.txt

*CAS NUMBER: 121-75-5
*BASE CHEMICAL NAME: MALATHION
*PRIMARY NAME: MALATHION
*CHEMICAL FORMULA: C10H19O6PS2
*STRUCTURAL FORMULA: (CH3O)2P(S)SCH(COOC2H5)CH2COOC2H5
*TOXICITY:
          LD50       orl       rbt          250      mg/kg
          LD50       orl       bwd          400      mg/kg
          LD50       orl       mus          190      mg/kg
          LD50       orl       rat          290      mg/kg
*SAX TOXICITY EVALUATION:
  THR: A human poison by ingestion.  An experimental poison by ingestion,
       inhalation, intraperitoneal, intravenous, intraarterial,
subcutaneous
       and possibly other routes.  Human systemic effects by ingestion.
Human
       mutagenic data.  An organic phosphate cholinesterase inhibitor-type
       insecticide.
*USES:
      This compound is used as an insecticide for fruits, vegetables,
ornamen-
 tals, household and livestock use.  It is also used as an acaracide, in
the
 control of flies and other insect pests in animal and poultry houses, in
the
 control of adult mosquitoes in public health programs, in the control of
human
 body and head lice and in flea and tick dips.  It is used in veterinary
medi-
 cine as an ectoparasiticide.
*COMMENTS:
      This compound is less toxic to humans than other anticholinesterase
agents
 because it is metabolized in the liver to an inactive form [102].  Humans
may
 be more susceptible to the toxic effects of this compound than rats [151].


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