[WTI-trainee] 9.24 | Mrs. Hepsa Ely Silliman Memorial Lectureship with Cori Bargmann

[Wu Tsai Institute News]

Cori Bargmann, PhD, will give the Mrs. Hepsa Ely Silliman Memorial Lecture<https://medicine.yale.edu/news-article/silliman-lecture-to-feature-neurobiologist-cori-bargmann-on-sept-24/> entitled, "One Brain, Many Behaviors: The Fascinating World of Internal States" on Tuesday, September 24, 2024, at 12:00 PM at the Mary S. Harkness Auditorium at SHM, 333 Cedar Street, poster attached.

The Yale Silliman Lectureship held once a year, was established in 1901. Its long history has brought many distinguished natural scientists to Yale. Lecturers are selected by a University-wide committee but are hosted by one Department, in this case, the Department of Neuroscience. Cori Bargmann is the Torsten N. Wiesel Professor and head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior at The Rockefeller University. Her research studies the relationships among genes, experience, and behavior in the nematode C. elegans.

Following is the abstract for Bargmann's talk:

"How do genes and the environment interact to generate a variety of behaviors? How are behavioral decisions modified by context and experience? Neuroscience has reached a stage where these questions can be asked with great precision, and, in some cases, answered. The Bargmann lab has studied these questions in the nematode C. elegans, whose simple nervous system consists of only 302 neurons – yet the animal can move around, explore the environment, evaluate its social context, and learn from experience. Animal and human behavior is not fixed but is reversibly modified by internal motivational and emotional states. At the heart of these internal states are chemical neuromodulators such as serotonin, dopamine, and neuropeptides. Neuromodulators are highly conserved in evolution, with recognizable similar functions in different animals. By studying molecules like serotonin and neuropeptides in C. elegans, we have determined how they transiently 'rewire' the nervous system, allowing internal states to alter the way that information is processed. I will describe examples from social behaviors and sickness behaviors."


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